Objective:To observe the therapeutic effects of electrical acupuncture and auricular-plaster therapy for chronic fatigue syndrome(CFS).Method:64 CFS patients were randomly divided into two groups.32 cases in the treatment group were treated by the electrical acupuncture and auricular-plaster therapy,and 32 cases in the control group with oral hydrocortisone.Results:The total effective rates were respectively 93.75% in the treatment group and 75.00% in the control group,with a statistically significant difference between the two groups(P＜0.05).Conclusion:Electrical acupuncture and auricular-plaster therapy may show a better anti-fatigue effect than that of routine West drugs.