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目的：优化甘草多糖浸膏提取工艺。方法：采用单因素考察和响应面法相结合，对提取温度、提取时间、料液比3个关键因素进行优化分析。结果：建立了甘草多糖浸膏提取得率模型，模型r=0.99991，回归模型显著。其提取优化条件：提取温度为100℃，提取时间为2.25 h，料液比为1∶62。结论：在优化提取工艺条件下，甘草多糖浸膏得率为12.96%。“,”Objective: To optimize the extraction technology of polysaccharide extract in glycyrrhiza. Methods: The effect of three key factors for the yield of polysaccharide extract in glycyrrhiza such as extraction temperature, extraction time and ratio of glycyrrhiza and water, were analyzed by one-factor-at-a-time-technique method and response surface methodology. Results:The yield model for extracting polysaccharide extract in glycyrrhiza was build, and the variance of model is 0.99991, which shows remarkable model, and the best conditions gained is that the extraction temperature is 100 ℃, the extraction time is 2.25 h and that the ratio of glycyrrhiza and water is 1 ∶62. Conclusion: The extraction yield of polysaccharide extract in glycyrrhiza is 12.96%.