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目的探讨磷酸肌酸钠对手足口病患儿心肌损害的临床疗效,分析其对心肌的保护作用。方法选择本院就诊的手足口病并心肌损害患儿120例,随机分为治疗组和对照组,两组均常规给予抗病毒、抗感染以及对症等治疗,治疗组在常规治疗的基础上加用磷酸肌酸钠。依据年龄不同给予磷酸肌酸钠0.25~0.5 g静脉滴注,1次/d,疗程为7 d。比较治疗前后心电图、心肌酶学的变化,以及临床疗效。结果 2组患者治疗前后心电图与心肌酶都有明显的变化,治疗组变化明显,临床疗效优于对照组。结论磷酸肌酸钠在应用于手足口病患儿并心肌损坏中的保护作用疗效确切。
Objective To investigate the clinical effect of sodium creatine phosphate on myocardial damage in children with hand-foot-mouth disease and its protective effect on myocardium. Methods 120 cases of hand, foot and mouth disease and myocardial damage in our hospital were selected and randomly divided into treatment group and control group. Both groups were routinely given antiviral, anti-infective and symptomatic treatment. The treatment group was treated with conventional treatment With creatine phosphate. According to different age given phosphate sodium phosphate 0.25 ~ 0.5 g intravenous infusion, 1 / d, treatment for 7 d. Before and after treatment compared electrocardiogram, myocardial enzyme changes, and clinical efficacy. Results Before and after treatment, electrocardiogram and myocardial enzyme had obvious changes in both groups, the treatment group changed significantly, and the clinical curative effect was better than that of the control group. Conclusion The efficacy of sodium creatine phosphate in the treatment of children with hand-foot-and-mouth disease and myocardial damage is indeed effective.