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许多研究表明人类对血吸虫的免疫力是通过重复感染逐渐获得的。因此,抗血吸虫疫苗从理论上说是可行的。由于人类使用活疫苗以及制备足够数量减毒活疫苗的困难,使非活性或修饰的抗原疫苗备受欢迎。研究表明日本血吸虫和曼氏血吸虫谷胱甘肽巯基转移酶(GST)是很有潜力的疫苗抗原。曼
Many studies show that human immunity to schistosomes is gradually obtained by repeated infections. Therefore, anti-schistosome vaccine is theoretically feasible. Inactivated or modified antigen vaccines are becoming popular due to the difficulties of using live vaccines and preparing a sufficient number of live attenuated vaccines for humans. Studies have shown that Schistosoma japonicum and Schistosoma mansoni glutathione-S-transferase (GST) are potential vaccine antigens. Man