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为了解福建省人群病毒性肝炎流行特征 ,福建省于 1992年进行五型病毒性肝炎感染的血清流行病学调查。采用多阶段分层整群随机抽样法 ,采集福建省疾病监测点自然人群的 12 37户家庭中 1～ 59岁居民血样本 380 9份。采用 RIA法检测 HBs Ag、抗 - HBs、抗 - HBc,采用 EIA法检测抗 - HAV、抗 - HCV、抗 - HDV、抗 - HEV和 HBe Ag。结果显示各标化流行率为 HAV 76.60 %、HBV77.2 6%、HCV 3.99%、HDV 2 .10 %、HEV 18.80 %、HBs Ag 17.2 5%、抗 - HBs 34 .33%、抗 - HBc68.58%、HBe Ag 8.4 2 %。农村 HAV、HBV、HEV流行率均高于城市。 HBs Ag流行率出现儿童峰和成人峰而且男性高于女性。 HBV和 HEV感染有明显的家庭聚集性。青壮年 HEV流行率高 ,城市儿童 HAV流行率低。提示福建省是 HAV、HBV、HCV、HEV的高流行区。预防甲、乙型肝炎病毒感染最有效策略是免疫接种甲、乙型肝炎疫苗。
To understand the epidemiological characteristics of viral hepatitis in Fujian Province, Fujian Province conducted a serological epidemiological investigation of five types of viral hepatitis in 1992. A total of 3809 blood samples were collected from 12 to 59-year-old residents of 12 37 households in the natural population at the disease surveillance sites of Fujian Province using multistage stratified cluster random sampling. The anti - HAV, anti - HCV, anti - HDV, anti - HEV and HBeAg were detected by EIA. The anti - HBs, anti - HBs and HBsAg were detected by RIA. The results showed that the prevalence of each standard was HAV 76.60%, HBV77.2 6%, HCV 3.99%, HDV 2.10%, HEV 18.80%, HBs Ag 17.2 5%, anti-HBs 34.33%, anti-HBc68. 58%, HBe Ag 8.4 2%. The prevalence rates of HAV, HBV and HEV in rural areas were higher than those in cities. The prevalence of HBs Ag shows peaks of children and adults and is higher in males than females. HBV and HEV infections have significant family aggregation. The prevalence of HEV in young adults is high, and the prevalence of HAV in urban children is low. Tip Fujian Province is a high prevalence of HAV, HBV, HCV, HEV. Prevention of hepatitis A, hepatitis B virus infection is the most effective strategy for immunization A, hepatitis B vaccine.