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作者选择确诊断为特发性骨髓纤维化(IM)患者16名,其中男性9名、女性7名、年龄在45～75岁之间。探讨免疫机制在IM发病机理中的作用。免疫复合物存在与否系以中性多形核粒细胞免疫组化法和C_1q凝集抑制试验来判定。检查结果,用免疫组化法检查中性多形核粒细胞中的IgG,阳性为14/16;用C_1q凝集抑制试验检查血清,阳性为13/16;2例中性多形核粒细胞
The authors chose to confirm the diagnosis of idiopathic myelofibrosis (IM) in 16 patients, including 9 males and 7 females, aged 45 to 75 years old. To explore the role of immune mechanism in the pathogenesis of IM. The presence or absence of immune complex was determined by neutral polymorphonuclear neutrophil immunohistochemistry and C-1q agglutination inhibition test. The results of immunohistochemical examination of neutral polymorphonuclear neutrophils IgG, positive for 14/16; C_1q agglutination inhibition test for serum, the positive was 13/16; 2 cases of neutral polymorphonuclear neutrophils