患男,15岁。3年前因皮肤散在出血点在当地医院诊断为过敏性紫癜,给予强的松治疗效果不佳后查骨髓象示:巨核细胞缺如,诊断为获得性无巨核细胞性血小板减少性紫癜(AATP)。用康力龙及达那唑治疗3个月,出血点消退后自行停药,停药3月后因鼻衄入院。查体:颈部皮肤见散在出血点,浅表淋巴结未触及,胸骨无压痛,心、肺无异常,肝、脾肋下未触及。实验室检查:血象WBC3.4×10~9/L,L70.9％,G19.5％,Hb85g/L,PLT18×10~9/L,RC0.010;骨髓象:有核细胞增生欠活跃,粒:红(G:E)=0.32:1,粒系10.0％,红系31.5％,全片仅见1个颗粒巨,血小板零星偶见,骨髓小粒大多数以网状、淋巴等非造血细胞为主。诊断:再生障碍性贫血(AA),慢性型。继续给康力龙、达那唑并加用环孢霉素A治疗。3个月后复查骨髓象示:有核细胞增生活跃,G:E=2.53:1,粒系22.5％,红系42.5％,巨核细胞11个/2.3cm Male, 15 years old. 3 years ago due to skin scattered in the bleeding point at the local hospital diagnosed as Henoch-Schonlein purpura, giving prednisone treatment ineffective check bone marrow icon shows: megakaryocyte absence, diagnosis of acquired megakaryocytic thrombocytopenic purpura (AATP ). With Condorone and danazol treatment for 3 months, stopping bleeding after the withdrawal of their own withdrawal, withdrawal for 3 months after admission due to epistaxis. Physical examination: see the neck skin scattered in the bleeding point, superficial lymph nodes not touched, no tenderness of the sternum, heart, lung no abnormalities, liver, spleen ribs untouched. Laboratory tests: blood WBC3.4 × 10 ~ 9 / L, L70.9%, G19.5%, Hb85g / L, PLT18 × 10 ~ 9 / L, RC0.010; bone marrow: nucleocytosis less active , Granule: red (G: E) = 0.32: 1, 10.0% of granulocyte and 31.5% of erythrocyte. Only one granule was found on the whole piece, sporadic occasional platelets were found, most of the bone marrow granule were reticulocytes and lymphatic Mainly. Diagnosis: Aplastic anemia (AA), chronic type. Continued to Kang Lilong, danazol and add cyclosporin A treatment. 3 months after the review of bone marrow icon shows: active hyperplasia of nucleated cells, G: E = 2.53: 1, 22.5% of grain lines, erythroid 42.5%, megakaryocytes 11 /2.3cm