4种极性不同的常用溶剂—甲醇、乙醇、丙酮和二甲亚砜,研究了对双酚A(BPA)的SERS图谱增强的干扰。其中用甲醇作为溶剂时干扰BPA增强的最小。用金胶试剂作为SERS的增强试剂,通过改变增强试剂与样品及HNO3的不同配比,进一步确定对BPA的增强干扰程度最小的3种试剂的最佳配比,从而为BPA的痕量检测提供依据。同时探讨了BPA的两种结构类似物对BPA增强的干扰。 Four commonly used solvents of different polarities - methanol, ethanol, acetone and dimethyl sulfoxide, were investigated for enhanced interference with the SERS pattern of bisphenol A (BPA). Among them, the use of methanol as a solvent to interfere with BPA enhanced minimum. By using gold colloid as SERS enhancer, the optimum ratio of the three reagents with the least interference to BPA was further determined by changing the ratio of enhancer to sample and HNO3 to provide trace detection of BPA in accordance with. At the same time, the two structural analogues of BPA were studied to enhance BPA interference.