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一、本文报告了吉林省地区大骨节病人46例以碘~(131)测定甲状腺机能的结果,并加以简略的综合分析。二、在46例大骨节病人中成人42例,经测定甲状腺机能基本正常者为26人,佔61.9％;机能低下或偏低者15人,佔38.1％。8-10岁儿童4名,经测定甲状腺机能皆在正常范围内。三、根据吸碘~(131)曲线来看,本组病人普遍呈低平曲线,最高吸碘~(131)百分率在15％以下者佔39.2％全组平均值也僅18.4％,与国内资料正常人平均值36.2％比较,本组病人显著偏低,个别病人低至4.2％。四、本文尚将本组病人的平均吸碘~(131)曲线及4(?)小时平均排碘~(131)百分率与国内资料119名正常人,5名甲状腺功能低下之病人以及与本祖病人同时期测定的甲状腺中毒症病人作了对比,证明本组大骨节病成人的平均吸碘~(131)曲线非常接近于5例机能低下病人的曲线而大大低于正常人的曲线,证明了甲状腺机能状态偏低之情况。五、本组病人48小时尿内排碘百分率平均值为47％较国内资料正常人平均值40.7％稍高,符合于甲状腺机能偏低之结论,但变化程度不若甲状腺吸碘~(131)曲线之明显。六、虽然基础代谢率的测定显示不出甲状腺机能低下的情况,但因碘~(131)测定甲状腺机能的方法为直接测定法,准确性较大,故前者不足以否定后者的结果。
First, this paper reports the results of 46 cases of Kaschin-Beck disease in Jilin Province with iodine ~ (131) determination of thyroid function, and a brief summary of the results. Second, in 46 cases of adult patients with Kashin-Beck 42 cases, the determination of thyroid function was 26 normal people, accounting for 61.9%; low or low function of 15 people, accounting for 38.1%. 4 children aged 8-10 years, the determination of thyroid function are within the normal range. According to the curve of iodine uptake (131), the patients in this group generally showed a low-level curve, and the highest percentage of iodine up to 131% was below 15%, accounting for only 39.2%. The average value of the whole group was only 18.4% Normal average 36.2%, this group of patients was significantly lower, individual patients as low as 4.2%. Fourth, this article still the average patient iodine absorption curve (131) and 4 (?) Hours average iodine ~ (131) percentage and domestic data of 119 normal subjects, five patients with hypothyroidism and the ancestral Patients with thyroidosis at the same time the determination of patients compared to prove that this group of patients with Kashin-Beck average iodine uptake curve (131) is very close to the curve of 5 cases of patients with impaired and significantly lower than the normal curve, proved Thyroid status is low. Fifth, in this group of patients 48 hours, the average percentage of urinary iodine was 47%, slightly higher than the average of 40.7% in domestic data, which was in line with the conclusion that hypothyroidism was low. However, The obvious curve. Sixth, although the determination of basal metabolic rate showed no hypothyroidism, but the determination of thyroid function by iodine ~ (131) method for the direct determination of the method, the accuracy of the larger, so the former is not enough to deny the latter results.