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苯丙烯酸类化合物的苯环上m位羟基取代后的化合物有耐缺氧活性。p及m位同时有羟基取代后无活性。其他有耐缺氧活性的化合物为:苯环上有一个甲氧基取代或在侧链的α位上有芳香环取代的化合物。
Compounds substituted with the m-position hydroxyl group on the benzene ring of the phenyl acrylic compound have hypoxia-tolerant activity. There is no activity of p and m after hydroxyl substitution. Other compounds having hypoxia-tolerant activity are: a methoxy group substituted on the benzene ring or an aromatic ring substituted on the? -position of the side chain.