通过检测尿中的某些代谢物的含量来诊断癌症是人们多年来追求的目标,具有这样特性的代谢物被称为肿瘤标志物(tumour marker).人们已经发现,尿中修饰核苷(modifiednucleoside)含量的升高与某些恶性肿瘤相联系,并已证明修饰核苷含量的升高源于转移RNA,在肿瘤的作用下转移RNA的周转速度增高从而释放出修饰核苷.初步研究表明,通 Diagnosing cancer by measuring the content of certain metabolites in urine is a goal pursued for many years. Metabolites with such characteristics are called tumour markers. It has been found that modified nucleosides in urine. ) The increase in the level is associated with certain malignancies, and it has been shown that the increase in modified nucleoside content is due to the transfer of RNA, which increases the turnover rate of the transferred RNA under the action of the tumour to release modified nucleosides. Preliminary studies have shown that through