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1979年至1989年,我院共收治绒癌患者132例,其中继发于足月产后的绒癌37例,占28.0%.本文对37例足月产后绒癌患者进行了回顾性分析和随访.随访率为94.6%.足月产后绒癌的临床症状以产后不规则阴道流血最常见,占86.5%.癌肿易早期发生全身转移,肺转移最多见,其次为脑转移和阴道转移.临床Ⅰ、Ⅱ期患者的完全缓解率为90.9%.Ⅲ、Ⅳ期患者完全缓解率为46.2%.本组5年生存率为69.6%,Ⅲ、Ⅳ期者预后则较差.因此,对于足月产后绒癌应早期诊断并仔细查明肿瘤转移情况,治疗则以联合化疗及手术为宜.
From 1979 to 1989, 132 cases of choriocarcinoma were admitted to our hospital, including 37 cases of choriocarcinoma secondary to full-term postpartum (28.0%) .This retrospective analysis and follow-up of 37 cases of full-term postnatal choriocarcinoma .The follow-up rate was 94.6% .The clinical symptoms of full-term post-operative choriocarcinoma were the most common vaginal bleeding in postpartum period, accounting for 86.5% .Cancer was the most common cause of systemic metastasis, lung metastasis, followed by brain metastasis and vaginal metastasis. The complete remission rate was 90.9% in stage Ⅰ and stage Ⅱ patients, and the complete remission rate was 46.2% in stage Ⅲ and stage Ⅳ.The 5-year survival rate was 69.6% in this stage, and the prognosis in stage Ⅲ and Ⅳ was poor.Therefore, Postpartum choriocarcinoma should be diagnosed early and carefully identify the tumor metastasis, the treatment is combined with chemotherapy and surgery is appropriate.