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目的了解新疆维吾尔自治区乌鲁木齐市某社区维吾尔族和汉族育龄期妇女碘营养水平及其差异。方法选取2013年5月在乌鲁木齐某社区进行甲状腺疾病流行病学调查的2 080例受试者中,资料完整的585例女性受试者为研究对象,年龄为18~45岁。按照不同民族,将其分为维吾尔族组(n=326)与汉族组(n=259)。回顾性分析2组受试者人体质量指数(BMI)、颈围、腹围、促甲状腺激素(TSH)、甲状腺球蛋白抗体(TgAb)、甲状腺过氧化物酶抗体(TPOAb)水平等一般临床资料,采用尿中碘的砷铈催化分光光度法检测尿碘水平。本研究遵循的程序符合新疆维吾尔自治区人民医院伦理委员会制定的伦理学标准,得到该委员会批准,并与受试者签署临床研究知情同意书。结果(1)维吾尔族组受试者BMI和腹围,均大于汉族组受试者,2组比较,差异均有统计学意义(t=7.015、7.104,P<0.001)。维吾尔族组和汉族组受试者的年龄、颈围及TSH、TgAb和TPOAb水平比较,差异均无统计学意义(P>0.05)。(2)维吾尔族组、汉族组受试者尿碘水平中位数分别为133.8μg/L(34.1~568.2μg/L)和131.7μg/L(27.7~513.6μg/L),二者比较,差异无统计学意义(Z=-0.156,P=0.876)。维吾尔族组、汉族组受试者碘缺乏、碘适量、碘超足量及碘过量构成比比较,差异无统计学意义(χ~2=1.556,P=0.669)。结论新疆维吾尔自治区乌鲁木齐市某社区维吾尔族、汉族育龄期部分妇女存在碘缺乏,维吾尔族和汉族育龄期妇女碘营养状况无明显差异。
Objective To understand the iodine nutrition level and its difference between Uyghur and Han women of childbearing age in a certain community in Urumqi, Xinjiang Uygur Autonomous Region. Methods Among 2 080 subjects who conducted epidemiological investigation of thyroid disease in a community in Urumqi in May 2013, 585 female subjects with complete data were selected as study subjects, aged from 18 to 45 years. According to different ethnic groups, it is divided into Uygur group (n = 326) and Han group (n = 259). The clinical data such as body mass index (BMI), neck circumference, abdominal circumference, thyroid stimulating hormone (TSH), thyroglobulin antibody (TgAb) and thyroid peroxidase antibody (TPOAb) , Urinary iodine arsenic cerium catalytic spectrophotometry urine iodine levels. The procedure followed in this study was in accordance with the ethical standards formulated by Ethnographic Committee of People’s Hospital of Xinjiang Uygur Autonomous Region, which was approved by the committee and signed informed consent form of clinical research with the subjects. Results (1) The BMI and abdominal circumference of the Uygur group were significantly higher than those of the Han group. There were significant differences between the two groups (t = 7.015, 7.104, P <0.001). There was no significant difference in age, neck circumference, TSH, TgAb and TPOAb between Uygur and Han nationality subjects (P> 0.05). (2) The median urinary iodine level in the Uygur and Han nationality groups was 133.8μg / L (34.1 ~ 568.2μg / L) and 131.7μg / L (27.7 ~ 513.6μg / L), respectively. The difference was not statistically significant (Z = -0.156, P = 0.876). The Uygur group and Han group had no significant difference in iodine deficiency, iodine amount, iodine excess and iodine excess (χ ~ 2 = 1.556, P = 0.669). Conclusion Some women of childbearing age of Uygur and Han nationality in a certain community in Urumqi, Xinjiang Uygur Autonomous Region have iodine deficiency. There is no significant difference in iodine nutrition between Uyghur and Han women of childbearing age.