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目的了解大肝癌手术切除术后肝动脉、门静脉双路置泵化疗栓塞的安全性。方法23例大肝癌手术切除后,肝动脉及门静脉双路置泵,术后2周门静脉化疗连续5d,每月1疗程;术后3周肝动脉化疗栓塞,1~2月1疗程。结果与置泵有关的并发症3例,腹水漏1例,导管脱出2例。与化疗栓塞有关的并发症,包括严重消化道反应2例,白细胞计数明显减少3例,无1例发生严重的肝功能衰竭。结论细致、规范的操作是预防置泵并发症的关键。化疗栓塞个体化,可减少肝功能衰竭等严重并发症
Objective To understand the safety of hepatic arterial and portal vein chemoembolization with the dual-channel pump after surgical resection of large hepatocellular carcinoma. Methods Twenty-three patients with large hepatocellular carcinoma were treated with hepatic arterial and portal vein pumps. Two weeks after operation, portal vein chemotherapy was continued for 5 days and one course of treatment was given every month. Hepatic arterial chemoembolization was performed at 3 weeks after operation. He was treated for 1 to 2 months. Results There were 3 cases of complications associated with the pump, 1 case of ascites leakage, and 2 cases of catheter prolapse. Complications related to chemoembolization included severe gastrointestinal reactions in 2 cases, marked decrease in white blood cell count in 3 cases, and no severe liver failure in 1 case. Conclusion Detailed and standardized operation is the key to preventing the complications of pumping. Individualized chemoembolization reduces severe complications such as liver failure