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目的探讨荧光素钠眼底血管造影的不良反应发生率、相关因素。方法回顾性分析牡丹江医学院附属二院五官医院620例眼底荧光血管造影患者的一般情况;观察不良反应发生的相关原因。结果本组不良反应41例(发生率6.6%),其中皮肤荨麻疹17例,恶心11例,呕吐5例,咳嗽、打喷嚏5例,头晕、心悸、面色苍白、出冷汗2例,一过性晕厥1例。不良反应的发生与荧光素钠的生产厂家不相关,而与患者的年龄、性别因素有关。结论荧光素钠是一种相对安全的染色剂,发生的不良反应一般是轻中度的而且不留后遗症,不良反应的发生多与性别、年龄等个体因素有关。
Objective To investigate the incidence of adverse reactions of fluorescein sodium fundus angiography and related factors. Methods Retrospective analysis of 620 cases of fundus fluorescein angiography in the Second Affiliated Hospital of Mudanjiang Medical College Hospital, the general situation; to observe the causes of adverse reactions. Results There were 41 adverse reactions (6.6%) in this group, including 17 cases of skin urticaria, 11 cases of nausea, 5 cases of vomiting, 5 cases of cough and sneezing, 2 cases of dizziness, palpitation, paleness and cold sweat One case of syncope. The incidence of adverse reactions and sodium fluorescein manufacturer is not related to the patient’s age and gender factors. Conclusion Sodium fluorescein is a relatively safe staining agent, the adverse reactions are generally mild and without sequelae, adverse reactions occur more with gender, age and other individual factors.