邯郸煤矿井下职工泌尿系结石高发危险因素的流行病学研究

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目的:探索导致煤矿井下工人发生泌尿系结石的危险因素,并为制定预防措施提供科学依据。方法:采用病例对照的研究方法,以收治的薛村矿患有泌尿系结石的井下职工为病例组,共151例,男112例,女39例;另外随机选择居住于薛村矿周边地区、饮用同一水源并确诊未患泌尿系结石的居民作为对照组,共170例,男85例,女85例。以性别、年龄、工龄、体质指数(BMI指数)、饮食成分和结构、日均饮水量、日均饮酒量作为研究因素,使用Logistic回归分析计算各因素的比值比(OR值)和95%可信区间(95%CI)。结果:性别、BMI指数、饮食成分和结构、日均饮水量、日均饮酒量五个因素的差异有统计学意义(P<0.05)。其中性别的OR值为0.291,95%CI为0.118~0.720;BMI指数的OR值为5.532,95%CI为2.562~1.949;饮食成分和结构的OR值为2.350,95%CI为0.039~0.231;日均饮水量的OR值为0.101,95%CI为0.046~0.223;日均饮酒量的OR值为7.758,95%CI为3.368~17.874。结论:随着BMI指数及日饮酒量的增加,泌尿系结石的发病风险增加;蔬菜为主的饮食结构和日饮水量的增加可以减少泌尿系结石的发病风险;男性较女性发生泌尿系结石的风险更高。 Objective: To explore the risk factors that lead to urolithiasis in underground coal mine workers and to provide a scientific basis for making preventive measures. Methods: A case-control study was conducted in 151 cases of underground workers suffering from urolithiasis in Xuecun Mine, including 112 males and 39 females. In addition, they were randomly selected to live in the surrounding area of ​​Xuecun Mine, A total of 170 residents drinking water from the same source who were diagnosed as having no urinary stones were enrolled in the study. There were 85 males and 85 females. Logistic regression analysis was used to calculate the odds ratios (OR) and 95% of the odds ratios for each factor by gender, age, length of service, body mass index (BMI), diet composition and structure, daily drinking water, Letter interval (95% CI). Results: There were significant differences in five factors of gender, BMI index, diet composition and structure, average daily drinking volume and average daily drinking amount (P <0.05). The OR of sex was 0.291, the 95% CI was 0.118 ~ 0.720, the OR of BMI index was 5.532, and the 95% CI was 2.562 ~ 1.949. The OR of diet composition and structure was 2.350, and the 95% CI was 0.039 ~ 0.231. The OR of daily drinking water was 0.101, and the 95% CI was 0.046 ~ 0.223. The OR of daily drinking amount was 7.758, and the 95% CI was 3.368-17.874. Conclusions: With the increase of BMI index and daily drinking volume, the risk of urolithiasis increases. The increase of vegetable-based diet and daily drinking water can reduce the risk of urolithiasis. The incidence of urolithiasis is higher in males than in females Risks are higher.
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