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作者以平均45.5(15～68)岁的8(男4、女4)例心源性水肿患者为对象,研究重度充血性心(力)衰(竭)时体液潴留的机制。患者组中,缺血性心脏病2例,扩张型心肌病6例。各例均有气急、踝部凹陷性水肿、颈静脉扩张和肝肿大。症状和体征已有3～12(平均8)个月。5例有腹水,2例有胸水。心胸比率平均68%。两维超声心动图测定左室射血分数为31±4%。插入 Swan-Ganz 导管测定血流动力学参数。采用标准的同位素稀释法测定体内水、钠间隙和肾功能。血浆激素水平采用放射免疫法或者高压液相法测定。
The aim of this study was to investigate the mechanism of fluid retention during severe congestive heart failure (CHF) in patients with cardiogenic edema in 8 (4, 4) cases of 45.5 (15-68) years old. In the patient group, 2 were ischemic heart disease and 6 were dilated cardiomyopathy. Each case has shortness of breath, ankle depression edema, jugular vein dilatation and hepatomegaly. Symptoms and signs 3 ~ 12 (average 8) months. 5 cases had ascites, 2 cases had pleural effusion. Cardiothoracic ratio of 68% on average. Left ventricular ejection fraction measured by two-dimensional echocardiography was 31 ± 4%. Swan-Ganz catheter was inserted to measure hemodynamic parameters. Standard isotope dilution method for determination of body water, sodium space and renal function. Plasma hormone levels were measured by radioimmunoassay or high pressure liquid chromatography.