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卡-梅现象是一种以严重血小板减少、微血管溶血性贫血及消耗性凝血障碍为特征的血管性病变。婴幼儿好发,死亡率高。作者采用长春新碱成功治疗卡-梅现象新生儿1例。患儿为女性,出生时即发现右大腿巨大血管瘤,病变发展迅速并出现凝血障碍及血小板减少。糖皮质激素和普萘洛尔治疗无效后,患儿每天静滴红细胞、血小板及蛋白支持治疗。首次治疗失败和潜在的严重出血,使患儿在出生后第45天接受长春新碱治疗。治疗第1周,血管瘤即出现明显改善;第2周,患儿无需接受支持治
Card-May phenomenon is a vascular disease characterized by severe thrombocytopenia, microvascular hemolytic anemia and consumptive coagulopathy. Infants and children occur, high mortality. The authors used vincristine successfully card - Mei phenomenon in 1 newborn. Children were female, born at the discovery of the right thigh huge hemangioma, rapid development of the disease and the occurrence of coagulation disorders and thrombocytopenia. After corticosteroids and propranolol were ineffective, they received daily intravenous infusion of red blood cells, platelets and protein support. The first failure of treatment and potentially serious bleeding left the children under vincristine treatment 45 days after birth. The first week of treatment, hemangioma that significantly improved; the first two weeks, children without supportive treatment