卡介苗接种已广泛应用于预防结核菌感染,但接种后导致播散性感染而死亡是罕见的,常因免疫缺陷所致。本文报导1例18岁的男性患者,接种卡介苗6年后死于播散性卡介苗感染,他有巨噬细胞和T淋巴细胞功能异常。患者生于1960年12月,正常妊娠足月出生,双亲非近亲婚配,无结核家族史。婴儿期曾接种三联疫苗(百白破)和口服灰髓炎活疫苗均无不良反应。儿童 BCG vaccination has been widely used to prevent tuberculosis infection, but the death caused by disseminated infection after inoculation is rare, often due to immunodeficiency. This article reports a case of 18-year-old male patient, died of disseminated BCG infection 6 years after BCG vaccination, he has macrophages and T lymphocytes dysfunction. The patient was born in December 1960, born in full term normal pregnancy, non-relatives of the parents were married, without a family history of tuberculosis. There was no adverse reaction to infants who had been vaccinated with triple vaccine (diphtheriae) and live gray-turtle vaccine. child