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目的了解多重耐药菌(MDRO)感染分布,以便采取综合性干预措施。方法采用目标性监测方法,对某三甲医院住院患者送检的病原学标本检验结果进行回顾性分析。结果 2013年度,从该医院住院患者送检病原学标本中内共检出病原菌1 173株,含多重耐药菌216株,检出率为18.41%;2014年度共检出病原菌1 083株,含多重耐药菌293株,检出率27.05%。检出的MDRO主要是大肠埃希菌、肺炎克雷伯菌、金黄色葡萄球菌和鲍曼不动杆菌。MDRO感染患者主要分布在综合重症监护病房(ICU)、神经外科ICU和泌尿外科。结论该医院住院患者多重耐药菌感染比例较高,主要集中在ICU,应采取严格消毒隔离、实时监测和控制抗菌药物的应用等综合措施加以防控。
Objective To understand the distribution of multi-drug resistant bacteria (MDRO) in order to take comprehensive interventions. Methods A targeted surveillance method was used to analyze the etiological test results of inpatients in a top three hospital. Results In 2013, 1 173 strains of pathogens and 216 strains of multi-drug resistant bacteria were detected in etiological specimens of hospitalized patients in this hospital. The detection rate was 18.41%. A total of 1 083 pathogens were detected in 2014, 293 multi-resistant bacteria, the detection rate was 27.05%. The major MDROs detected were Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus and Acinetobacter baumannii. Patients with MDRO infection are predominantly in the Integrated Intensive Care Unit (ICU), Neurosurgery ICU, and Urology. Conclusions The inpatients in this hospital have a higher incidence of multi-drug resistant bacteria infection, mainly concentrated in the ICU, and should be controlled by comprehensive measures such as strict disinfection and isolation, real-time monitoring and control of the application of antimicrobial agents.