报告褶皱部位异色病样蕈样肉芽肿1例。患者女,39岁。因褶皱部位皮疹17年就诊。皮肤科检查:双侧腋下、肘窝、乳房皱襞、腹部、腹股沟、腘窝及足踝内侧对称鳞屑性网状斑片,其间可见点、片状色素减退,伴皮肤萎缩及毛细血管扩张。皮损组织病理检查:较多淋巴样细胞侵入表皮,部分核深染,可见Pautrier微脓肿样结构。免疫组化示CD8、CD3、CD4、CD5及CD7均阳性;CD20及CD30阴性。诊断:异色病样蕈样肉芽肿。 One case of mycosis mycosis fungoides was reported at the folds. Female patient, 39 years old. 17 years of treatment of rash due to folds. Dermatology examination: bilateral underarm, elbow fossa, breast fold, abdomen, groin, popliteal fossa and ankle medial scale scaly reticular patches, during which point, patchy pigment loss, with skin atrophy and telangiectasia. Skin lesions histological examination: more lymphoid cells invade the epidermis, part of the nuclear stained, visible Pautrier micro abscess-like structure. Immunohistochemistry showed CD8, CD3, CD4, CD5 and CD7 were positive; CD20 and CD30 negative. Diagnosis: Heterochromic Mycosis fungoides.