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目的探讨II型糖尿病合并脑血管意外的相关危险因素。方法将临床资料结合头颅CT或MRI确诊的40例II型糖尿病合并脑血管意外组(A组)和同期住院的42例糖尿病无脑血管意外组(B组)及44例无糖尿病脑血管意外组(C组)测定的血总胆固醇、甘油三酯、高密度脂蛋白和空腹血糖进行综合临床分析。结果A组甘油三酯、空腹血糖明显高于B组,A组和B组又明显高于C组;高密度脂蛋白均值降低,分组比较正好相反;三组胆固醇均值无显著性差异;A组比C组发病年龄提前,A组比B组容易并发高血压和冠心病,同时显示脑血管意外主要表现为缺血性脑梗塞。结论高血糖和以高甘油三酯、低高密度脂蛋白为主的脂代谢异常是II型糖尿病并发心脑血管病变的重要危险因素。
Objective To investigate the related risk factors of type 2 diabetes complicated with cerebrovascular accident. Methods Forty-two patients with type II diabetes mellitus complicated with cerebrovascular accident (group A) and 42 patients with diabetes mellitus without cerebrovascular accident (group B) and 44 patients with non-diabetic cerebrovascular accident who were hospitalized in the same period were analyzed with clinical data and cranial CT or MRI. (Group C) measured blood total cholesterol, triglycerides, high-density lipoprotein and fasting blood glucose clinical analysis. Results A group of triglycerides, fasting blood glucose was significantly higher than the B group, A group and B group was significantly higher than the C group; mean HDL decreased, the group compared with the opposite; the average of three groups of cholesterol was no significant difference; A group The age of onset was earlier than that in group C, and group A was more likely to develop hypertension and coronary heart disease than group B. At the same time, the main cause of cerebrovascular accident was ischemic cerebral infarction. Conclusions Hyperglycemia and abnormal lipid metabolism, which mainly consist of high triglyceride and low-density lipoprotein, are important risk factors of type 2 diabetes complicated with cardiovascular and cerebrovascular diseases.