作者通过11条清醒的感染性休克狗观察了酸碱平衡和血乳酸、丙酮酸的变化,严重感染后最先发生呼吸性碱中毒,以后随着呼吸功能受损程度的不同而有不同的发展趋势。肺损害不严重者将不出现呼吸性酸中毒,肺损害严重、有通气衰竭者将转为呼吸性酸中毒。随着休克的发展,在上述呼吸性酸碱失衡的基础上还会出现代谢性酸中毒。本实验显示,缺氧不是血乳酸增加的唯一原因。 The authors observed changes in acid-base balance and blood lactate, pyruvate through 11 conscious septic shock dogs, first with respiratory alkalosis after severe infection and later with different development depending on the extent of respiratory impairment trend. Severe lung damage will not occur respiratory acidosis, severe lung damage, ventilation failure will be converted to respiratory acidosis. With the development of shock, metabolic acidosis may occur on the basis of the above respiratory acid-base imbalance. This experiment shows that hypoxia is not the only reason for increased blood lactate.