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应用免疫组织化学ＡＢＣ法对９８例恶性小圆细胞肿瘤（ＭＳＲＣＴ）免疫组化表型及病理形态进行研究。结果表明：神经母细胞瘤、嗅神经母细胞瘤、原始神经外胚叶肿瘤、肺神经内分泌癌的免疫组化特征为ＮＳＥ阳性，而Ｄｅｓ阴性；未分化癌ＫＥＴ、ＥＭＡ、ＣＥＡ阳性；胚胎性横纹肌肉瘤ＭＧ、Ｖｉｍ、Ｄｅｓ呈阳性反应；尤文氏肉瘤Ｖｉｍ阳性，有些病例ＮＳＥ阳性；未分化滑膜肉瘤Ｖｉｍ阳性，部分病例ＫＥＴ、ＥＭＡ阳性；无色素性恶性黑色素瘤ＨＭＢ４５阳性；ＬＣＡ是恶性淋巴瘤特异性标记；ＨＣＧ、ＡＦＰ可作为精原细胞瘤的标记。
Immunohistochemical ABC method was used to study the immunohistochemical phenotype and pathology of 98 cases of malignant round cell tumor (MSRCT). The results showed that the immunohistochemical characteristics of neuroblastoma, olfactory neuroblastoma, primitive neuroectodermal tumor, and pulmonary neuroendocrine carcinoma were NSE-positive and Des-negative; KET, EMA, and CEA were positive in the undifferentiated carcinoma; embryonality Rhabdomyosarcoma MG, Vim, Des positive reaction; Ewing’s sarcoma Vim positive, in some cases NSE positive; undifferentiated synovial sarcoma Vim positive, some cases of KET, EMA positive; no pigmentation malignant melanoma HMB45 positive; LCA is malignant Lymphoid Tumor-specific markers; HCG, AFP can be used as a marker for seminoma.