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１５只健康杂种犬随机均分为Ⅰ、Ⅱ、Ⅲ组。三组犬分别前肢静脉一次性快速推注１ｍｌ／ｋｇ，对庆大霉素敏感的大肠杆菌混悬液１．８×１０１２个／ｍｌ制成感染性休克。随即从同一通道推注庆大霉素（４０００ｕ／ｋｇ）；并按组Ⅰ、Ⅱ、Ⅲ将丹参注射液（７ｇ／ｋｇ），地塞米松（１ｍｇ／ｋｇ），生理盐水（５ｍｌ／ｋｇ）加入５％ＧＮＳ１０００ｍｌ静滴，监测犬的血压、脉博、呼吸、尿量及存活时间。结果示：丹参注射液与地塞米松比较，感染性休克犬存活时间延长，存活率提高（ｐ＜０．０５）；且有较明显地升压，减慢心率，增加尿量的作用（ｐ＜０．０５），但对呼吸频率改变无差异（ｐ＜０．０５）。作者认为丹参具有抗犬感染性休克的作用，提示临床上对感染性休克患者应用丹参，可望提高存活率。
Fifteen healthy mongrel dogs were randomly divided into Ⅰ, Ⅱ and Ⅲ groups. Three groups of dogs, forelimb vein rapid bolus 1ml / kg, gentamicin-sensitive E. coli suspension 1.8 × 1012 / ml made of septic shock. Then, gentamycin (4000u / kg) was bolted from the same channel. Salvia miltiorrhiza injection (7g / kg), dexamethasone (1mg / kg), saline (5ml / kg) Add 5% GNS1000ml intravenous drip to monitor dog’s blood pressure, pulse, respiration, urine output and survival time. The results showed that compared with dexamethasone, Salvia miltiorrhiza injection prolonged the survival time of septic shock dogs and increased the survival rate (p <0.05); and more obvious effects of increasing blood pressure, slowing heart rate and increasing urine output (p <0.05), but no difference in respiratory rate (p <0.05). The authors believe that Salvia has dog-resistant septic shock, suggesting that clinical application of Salvia miltiorrhiza in patients with septic shock, is expected to improve survival.