论文部分内容阅读
目的观察丹参酮ⅡA磺酸钠注射液治疗不稳定型心绞痛的临床疗效和安全性。方法将60例患者分为对照组和治疗组各30例,对照组采用西药常规治疗;治疗组在对照组基础上加用丹参酮ⅡA磺酸钠注射液60 mg加入生理盐水或5%葡萄糖250 ml静脉滴注,每日1次,疗程均15 d。观察2组治疗前后心绞痛疗效、心电图ST-T改变、血脂变化及不良反应。结果治疗组与对照组比较,心绞痛疗效、心电图疗效及血脂改善均优于对照组(P<0.05)。结论在西药常规治疗基础上加用丹参酮ⅡA磺酸钠注射液治疗不稳定型心绞痛安全、有效。
Objective To observe the clinical efficacy and safety of tanshinone Ⅱ A sodium sulfonate injection in the treatment of unstable angina pectoris. Methods Sixty patients were divided into control group and treatment group, 30 cases in each group. The control group was treated with conventional western medicine. The treatment group was treated with 60 mg of tanshinone Ⅱ A sodium sulfonate injection and 250 ml of normal saline or 5% glucose on the basis of the control group. Intravenous instillation, once daily, the course of treatment is 15 d. Before and after treatment, angina pectoris, ECG ST-T changes, blood lipid changes and adverse reactions were observed. Results Compared with the control group, the curative effect of angina pectoris, the efficacy of electrocardiogram and the improvement of blood lipids in the treatment group were better than those in the control group (P <0.05). Conclusion It is safe and effective to add tanshinone Ⅱ A sodium sulfonate injection in the treatment of unstable angina pectoris on the basis of conventional western medicine.