Dubin—Johnson练合征(DJS)件肝细胞先天性代谢异常所致的疾患,发病机制尚不十分清楚。国内自1958年起对本病临床表现及光镜病理变化开始报导。本文将肝组织电镜观察结果报告如下: 一、材料与方法:临床表现为原因不明黄疸的患者,肝穿活检取材。一份经福尔马林固定、石腊包埋、切片HE染色,光镜观察。另一份经戌二醛 Dubin-Johnson’s Syndrome (DJS) is a disease caused by congenital metabolic abnormalities in liver cells. The pathogenesis is not yet clear. Domestic reports on the clinical manifestations and pathological changes of light microscopy have been reported since 1958 in China. This article will report the liver tissue electron microscopy results are as follows: First, materials and methods: Clinical manifestations of patients with unexplained jaundice, liver biopsy material. A formalin-fixed, paraffin-embedded, sliced ​​HE staining, light microscopy. Another fraction of glyoxal