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我科对10例淋巴瘤伴乙型肝炎病毒（HBV）感染的患者进行化疗，探索化疗所致肝损害及对HBV的影响。结果有6例出现肝功能明显损害，其中2例出现重症肝炎（1例抢救成功，1例死亡）。提示：对伴HBV感染的淋巴瘤患者进行化疗时应慎用皮质激素，化疗停止后要逐渐减量，以防止重症肝炎发生。化疗前行HBV血清学检查有重要临床意义。
In our department, 10 patients with lymphoma and hepatitis B virus (HBV) infection were treated with chemotherapy to explore the effects of chemotherapy-induced liver damage and HBV. Results Six cases showed obvious damage to liver function, including two cases of severe hepatitis (one case was successfully treated and one case died). Tip: With HBV infection in patients with lymphoma chemotherapy should be cautious of corticosteroids, chemotherapy should be gradually reduced after the stop to prevent the occurrence of severe hepatitis. HBV serology before chemotherapy has important clinical significance.