优化大孔吸附树脂分离纯化人参籽皂苷工艺。通过静态吸附解析试验筛选出大孔吸附树脂型号AB-8,上样pH 8~9,洗脱剂为50%乙醇溶液,动态试验优化分离纯化人参籽皂苷的工艺条件。结果表明,吸附时,上样质量浓度为3mg/mL,上样速度为1.0 mL/min,上样量为3倍柱体积,洗脱速率为1.5 mL/min,洗脱量为3.5倍柱体积时,AB-8对人参籽皂苷有较好的分离纯化效果。分离后人参籽皂苷浓度提高大约2.4倍。 Optimization of Macroporous Adsorption Resin for Separation and Purification of Ginseng Saponins. The macroporous adsorption resin model AB-8 was screened by static adsorption analysis test, the sample was loaded with pH 8-9, and the eluent was 50% ethanol. The dynamic conditions were optimized by dynamic test. The results showed that the loading volume was 3 mg / mL, the loading speed was 1.0 mL / min, the loading volume was 3 column volumes, the elution rate was 1.5 mL / min and the elution volume was 3.5 column volumes , AB-8 on ginsenosides have better separation and purification. After separation, ginseng seed saponin concentration increased about 2.4 times.