急性上消化道大出血是临床常见急症,由于数小时内失血超过1000ml或循环血容量的20%可引起低血容量休克,导致急性周围循环衰竭、急性肾功能衰竭甚至多系统功能衰竭而死亡。但引起皮层盲、心肌梗塞、脑梗塞、精神异常极少见,为加深了解,本文结合国内文献报道11例及我院遇见2例共13例,简述分析。一、上消化道出血并皮层盲患者,男,45岁,因呕血、解黑粪6小时于1988年10月3日入院。既往有十二指球部溃疡病史,入院当天经输血、止血等治疗后仍呕血2次,为暗红色血液伴血块,量约400ml,解黑 Acute upper gastrointestinal bleeding is a common clinical emergency, due to the loss of blood within 1000 hours or 20% of circulating blood volume can cause hypovolemic shock, leading to acute peripheral circulatory failure, acute renal failure and even multiple system failure and death. However, it is very rare to cause cortical blindness, myocardial infarction, cerebral infarction and mental abnormalities. In order to deepen the understanding, this article combines 11 cases reported in the domestic literature and 13 cases 2 cases met in our hospital. First, the upper gastrointestinal bleeding and cortical blind patients, male, 45 years old, due to hematemesis, solution of black manure 6 hours on October 3, 1988 admission. In the past, there was a history of twelve finger ulcers. On the day of admission, hematemesis was still vomited 2 times after transfusion, hemostasis and so on. It was dark red blood with blood clots, about 400ml,