1例67岁男性患者因牙龈炎口服奥硝唑(1.0 g,1次/d)、头孢拉啶(0.5 g,3次/d)和对乙酰氨基酚(0.5 g,2次/d)。3 d后疼痛减轻,但出现头晕、头痛及乏力症状。停用头孢拉啶和对乙酰氨基酚,继续服用奥硝唑。4 d后患者突然出现精神异常,症状昼轻夜重,脑电图检查示α波频率变慢,出现散在不规则θ波,诊断为谵妄。停用奥硝唑,给予氟哌啶醇5 mg,1次/d肌内注射;维生素B_6 0.2 g、三磷酸腺苷40 mg、辅酶A 200 U以及维生素C 2.0 g加入10%葡萄糖氯化钠注射液1000 ml中静脉滴注,1次/d;奥氮平5~10 mg,2次/d口服。3 d后患者神志恢复,停用氟哌啶醇;奥氮平减量至0.25 g,1次/d口服。治疗第6天患者头晕、头痛及乏力消失,体力恢复,脑电图检查正常。第7天停用抗精神病药。随访3个月余,患者精神状态正常。 One 67-year-old male patient was given ornidazole (1.0 g once daily), cefradine (0.5 g three times daily), and paracetamol 0.5 g twice daily for gingivitis. 3 days after the pain relief, but dizziness, headache and fatigue symptoms. Disable cefradine and acetaminophen, continue to take ornidazole. After 4 days, the patient suddenly experienced mental abnormalities. The symptoms were light and heavy at daytime. The frequency of α wave was slowed down by electroencephalogram examination. The scattered irregular θ wave appeared and the diagnosis was delirium. Ornidazole was discontinued, 5 mg of haloperidol was given intramuscularly once a day, and vitamin B 6 0.2 g, adenosine triphosphate 40 mg, coenzyme A 200 U and vitamin C 2.0 g were added into 10% glucose and sodium chloride injection 1000 ml intravenous infusion, 1 / d; olanzapine 5 ~ 10 mg, 2 times / d orally. After 3 days, the patient recovered consciousness and stopped the use of haloperidol. Olanzapine was orally dosed to 0.25 g once daily. On the 6th day of treatment, the patients were dizzy, their headache and fatigue disappeared, physical recovery and EEG examination were normal. On the seventh day antipsychotics disabled. Follow-up more than 3 months, the patient’s mental state was normal.