血栓闭塞性脉管炎是周围血管的一种慢性持续性进行性的血管炎症疾病。其主要病变为血栓形成,管腔闭塞,最后导致肢体缺血、坏死。早期诊断依据 1.发病特点:在我国北方各省多见,男性居多,发病年龄多在20～45岁之间,好发于下肢足趾部。 2.病史:一般认为发病前有长期或重度吸烟史,局部外伤史,患肢受寒凉、潮湿及冻伤史,其中有一部分人伴有静脉炎的病史。 Thromboangiitis obliterans is a chronic persistent progressive vascular inflammatory disease of the peripheral blood vessels. The main lesion is thrombosis, lumen occlusion, and finally lead to limb ischemia and necrosis. Early diagnosis based on 1 incidence characteristics: more common in the provinces of northern China, mostly men, more than the onset age of 20 to 45 years old, occur in the lower extremity toe. 2. History: Generally considered before the onset of long-term or severe smoking history, history of local trauma, limb affected by cold, damp and frostbite history, some of whom have a history of phlebitis.