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肝纤维化是各种致病因子引起的肝脏损害和炎症反应,是肝脏对慢性损伤修复和愈合的结果,即纤维结缔组织广泛的增生和沉积.研究已证实,肝纤维化形成的本质是肝脏内细胞外基质(extracellular matrix,ECM)合成和降解失衡,表现为ECM大量沉积.ECM的主要成分是胶原.
基质金属蛋白酶及其抑制因子与肝纤维化关系的研究近况
【摘 要】
：
肝纤维化是各种致病因子引起的肝脏损害和炎症反应,是肝脏对慢性损伤修复和愈合的结果,即纤维结缔组织广泛的增生和沉积.研究已证实,肝纤维化形成的本质是肝脏内细胞外基质(e
【出 处】
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内科
【发表日期】
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2004年期
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