Background Coronary heart disease (CHD) has become the third leading cause of death among Chinese adults.It is acknowledged that cholesterol has a strong relation with CHD.However,at present it is not clear which nurse-based health education strategies are effective in helping reduce serum cholesterol levels for patients with CHD.Methods A meta-analysis study was used to locate evidence supporting the effective health education methods for lowering cholesterol level in patients with CHD.Results In total,eight studies met the inclusion criteria.Telehealth education method reduced total cholesterol by 0.33 mmol/L,while consulting health education strategy helped to reduce total cholesterol by 0.41 mmol/L.Conclusions Nurse-based health education strategies using counselling sessions and telephone help to lower serum cholesterol level for patients with CHD.Future studies need to be conducted on the cost-effectiveness of this approach.