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目的探讨恶性肿瘤外周血T淋巴细胞亚群的表达及其临床意义。方法应用酶免染色技术对50例恶性肿瘤患者外周血T淋巴细胞亚群进行测定,并与50例健康人T淋巴细胞亚群的含量进行了比较分析。结果恶性肿瘤患者CD下降(P<0.01),CD8升高(P<0.01),CD4/CD8比值下降(P<0.01)。结论提示恶性肿瘤患者免疫平衡失调,细胞免疫功能下降。
Objective To investigate the expression and clinical significance of peripheral blood T lymphocyte subsets in malignant tumors. Methods Peripheral blood T-lymphocyte subsets were measured in 50 patients with malignant tumors using enzyme immunostaining technique, and compared with 50 healthy individuals’ T-lymphocyte subsets. Results The CD of patients with malignant tumors decreased (P<0.01), CD8 increased (P<0.01), and the ratio of CD4/CD8 decreased (P<0.01). Conclusions suggest that the imbalance of immune balance in patients with malignant tumors, decreased cellular immune function.