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作者用套式ＰＣＲ检测２５例丙型病毒性肝炎（丙肝）患者血清和外周血单核细胞（ＰＢＭＣ）中ＨＣＶ—ＲＮＡ，结果显示血清阳性２１例，ＰＢＭＣ阳性１８例，表明在大部分丙肝患者ＰＢＭＣ中有ＨＣＶ—ＲＮＡ的存在。且急性丙肝患者ＰＢＭＣ中ＨＣＶ—ＲＮＡ阳性率明显低于慢性丙肝患者，提示ＰＢＭＣ中ＨＣＶ—ＲＮＡ的存在可能与感染ＨＣＶ后的慢性化有关。
The authors used nested PCR to detect HCV-RNA in serum and peripheral blood mononuclear cells (PBMCs) of 25 patients with hepatitis C (HCV). The results showed that 21 cases were seropositive and 18 cases were PBMC positive, indicating that in most hepatitis C patients The presence of HCV-RNA in PBMCs. The positive rate of HCV-RNA in PBMC of patients with acute hepatitis C was significantly lower than that of patients with chronic hepatitis C, suggesting that the presence of HCV-RNA in PBMC may be related to the chronicity of infection after HCV infection.