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目的 :采用高效液相色谱法检测氨氯西林胶囊中有关物质含量。方法 :以 0 0 2mol/lKH2 PO4 缓冲液 (pH =5 0 ) -乙腈 ( 72∶2 8)为流动相 ,检测波长为 2 2 5nm。结果 :有关物质量为 1 73 6% (n =6)。结论 :方法重现性好 ,结果满意。
Objective: To determine the content of related substances in amoxicillin capsules by high performance liquid chromatography. Methods: The mobile phase consisted of 0 0 2mol / L KH2PO4 buffer (pH = 50) - acetonitrile (72: 2 8) and the detection wavelength was 225 nm. Results: The relevant substance was 1 73 6% (n = 6). Conclusion: The method has good reproducibility and satisfactory results.