论文部分内容阅读
目的探讨糖尿病前期和糖尿病的相关因素。方法根据ADA 2003年分类标准,对糖尿病前期和糖尿病相关因素进行Logistic回归分析。总共纳入204名对象,正常血糖66名,糖尿病前期100例,糖尿病患者38例。结果 3种不同的血糖状态在TG、胰岛素抵抗指数(HOMA-IR)、胰岛素分泌指数(HOMA-β)、血清总免疫球蛋白E(IgE)和C-RP的分布差异均具有统计学意义(P<0.05或P<0.01);多变量Logistic回归分析结果表明,IR与IS是糖尿病前期及糖尿病的危险因子(P<0.05)。结论 HOMA-IR与HOMA-β是公认的糖尿病的危险因子。
Objective To investigate the related factors of pre-diabetes and diabetes. Methods According to the ADA 2003 classification criteria, Logistic regression analysis was performed on pre-diabetes and diabetes-related factors. A total of 204 subjects were enrolled, with 66 normal blood glucose, 100 pre-diabetes, and 38 diabetic patients. Results The distributions of TG, insulin resistance index (HOMA-IR), insulin secretion index (HOMA-β), serum total immunoglobulin E (IgE) and C-RP in three different blood glucose levels were statistically significant P <0.05 or P <0.01). Multivariate Logistic regression analysis showed that IR and IS were risk factors of pre-diabetes and diabetes (P <0.05). Conclusion HOMA-IR and HOMA-β are recognized as risk factors for diabetes mellitus.