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甲型病毒性肝炎(简称甲肝)的肝细胞损害机制尚未明确。一些学者报告的实验结果提示:甲肝病毒并不直接导致肝细胞的病理改变,而可能由机体对感染病毒的肝细胞的免疫应答而引起。目前,国内有关甲肝患者机体细胞免疫状态的研究报告甚少。本文采用抗人淋巴细胞的单克隆抗体,检测了甲肝患者外周血淋巴细胞亚群,旨在了解甲肝患者机体细胞免疫和肝细胞损害机制。现将结果报告如下:
Hepatitis A virus (referred to as hepatitis A) liver cell damage mechanism is not yet clear. Some scholars report the experimental results suggest that: hepatitis A virus does not directly lead to the pathological changes of liver cells, but may be caused by the body’s immune response to the virus-infected liver cells. At present, there are few reports on the cellular immune status of hepatitis A patients in China. In this paper, anti-human lymphocyte monoclonal antibody was used to detect peripheral blood lymphocyte subsets in patients with hepatitis A, in order to understand the mechanism of cellular immunity and liver cell damage in patients with hepatitis A virus. The results reported below: