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目的 拟探讨青年人胃癌的生物学行为及有针对性的诊治措施。方法 回顾性总结经外科治疗的30例30岁以下青年人胃癌的临床表现、肉眼形态、组织学类型、浸润深度、淋巴结转移及预后等,并对其临床特点加以分析。结果 临床表现无特异性,多为分化较差的浸润型癌,转移早、进展快、病期晚、预后差。结论 青年人胃癌恶性度高,合理选择手术方式及以手术为中心的综合治疗有助于提高生存率,而更主要的是掌握其临床特点,早诊早治。
Objective To explore the biological behavior and targeted diagnosis and treatment of gastric cancer in young people. Methods The clinical manifestations, gross morphology, histological types, depth of invasion, lymph node metastasis, and prognosis of 30 gastric cancer patients younger than 30 years old underwent surgical treatment were retrospectively reviewed. Clinical characteristics were analyzed. Results The clinical manifestations were non-specific and mostly poorly differentiated invasive carcinomas with early metastasis, rapid progression, late stage, and poor prognosis. Conclusions The high degree of malignancy of gastric cancer in young people, rational choice of surgical methods and comprehensive treatment with surgery as the center can help improve the survival rate, but more important is to grasp its clinical characteristics, early diagnosis and early treatment.