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目的观察纤维蛋白胶抗生素复合体治疗深部创口的C-反应蛋白变化。方法采用临床病例对照研究方法进行研究。结果(1)试验组组内术后不同时间内C-反应蛋白均不同(P<0.05),术后24h的C-反应蛋白最高,以后随着治疗时间延长,C-反应蛋白逐渐下降。(2)试验组和对照组术后24h和术后24d的C-反应蛋白差异无统计学意义(P>0.05),其余不同时间试验组和对照组C-反应蛋白有差别(P≤0.005),试验组C-反应蛋白均比对照组低。结论我们研制的纤维蛋白胶抗生素复合体治疗深部创口有较好的临床效果。
Objective To observe the changes of C-reactive protein in fibrin glue antibiotic complex for treatment of deep wound. Methods The clinical case-control study was conducted. Results (1) C-reactive protein was different at different time points in the experimental group (P <0.05), and C-reactive protein was the highest at 24 hours after operation. C-reactive protein decreased gradually with the prolonged treatment time. (2) There was no significant difference in C-reactive protein between the experimental group and the control group at 24 and 24 hours after operation (P> 0.05), while the difference of C-reactive protein between the experimental group and the control group at different times (P≤0.005) , The experimental group C-reactive protein lower than the control group. Conclusion We developed fibrin glue antibiotic complex treatment of deep wounds have a good clinical effect.