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Pilocarpine 降眼压作用确切,副作用少,价格便宜,自1877年Weber 应用以来已有100年的历史。但有作用时间短,每日点眼次数多,患者难坚持及药效不能保持恒定的缺点。为此近年来研制应用合成高分子膜,能使Pilocar-pine 持久连续地进入结膜囊内。材料与制作Ocusert 为白色扁平富于柔软性的椭园形膜,制品分Ocusert Pilo-20和Pilo—40二种。P—20为13.4×5.7mm 大小,由三层构成。中部为Pilocarpine 和海藻酸混成膜样物,其两侧
Pilocarpine has an ocular hypotensive effect with less side effects and lower prices, and has been around 100 years since Weber was first introduced in 1877. However, there are short acting time, daily number of eye contact, patients difficult to maintain and efficacy can not be maintained shortcomings. In recent years, research and application of synthetic polymer membrane, can make Pilocar-pine long-term continuous into the conjunctival sac. Materials and Fabrication Ocusert is a white flat, pliable, oval-shaped membrane with two products, Ocusert Pilo-20 and Pilo-40. The P-20 is 13.4 × 5.7mm in size and consists of three layers. Central Pilocarpine and alginate mixed film samples, both sides