Refetoff综合征是Refetoff等氏1967年最初发现的新甲状腺疾病,通常称为Refet-off综合征或甲状腺激素不应症。本病是指在血液中虽然存在甲状腺激素,但由于未梢组织对激素感受性异常而不能发挥其作用的一种病症,因此也可理解为类似激素受体异常症。甲状腺激素的受体几乎存在于体内的所 Refetoff syndrome is a new thyroid disease originally discovered by Refetoff et al. In 1967, commonly referred to as Refet-off syndrome or thyroid hormone syndrome. The disease refers to the presence of thyroid hormones in the blood, but the tip of the organization because of abnormal hormonal abnormalities and can not play a role in the disease, it can be understood as similar to hormone receptor abnormalities. Thyroid hormone receptor almost exists in the body