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目的:探讨代谢综合征(MS)对急性心肌梗死患者冠状动脉病变及预后的影响。方法:连续入选2006-01-01-2006-12-31首次诊断为急性ST段抬高型心肌梗死的患者84例,分为MS组及非MS组,比较2组患者的临床资料。结果:MS组血TG浓度及体质指数明显高于非MS组(P<0.001),高血压及糖尿病患病率显著高于非MS组(P<0.001);而2组在年龄、空腹血糖、HDL-C、LDL-C、TC及尿酸等差异无统计学意义;病变血管数目、进行冠状动脉搭桥术的比率及置入支架的总长度差异亦无统计学意义。logistic回归分析未能证明MS是不良事件发生的独立预测因子。结论:MS在急性心肌梗死中患者普遍存在,MS对急性心肌梗死冠状动脉病变严重程度及预后无明显影响。
Objective: To investigate the effect of metabolic syndrome (MS) on coronary artery disease and prognosis in patients with acute myocardial infarction. Methods: A total of 84 patients with acute ST-segment elevation myocardial infarction were selected for the first time in 2006-01-01-2006-12-31. The patients were divided into MS group and non-MS group. The clinical data of two groups were compared. Results: The blood TG level and body mass index in MS group were significantly higher than those in non-MS group (P <0.001). The prevalence of hypertension and diabetes in MS group was significantly higher than that in non-MS group (P <0.001) HDL-C, LDL-C, TC, uric acid and other differences were not statistically significant; the number of vascular lesions, the rate of coronary artery bypass grafting and the total length of stent placement was also no significant difference. Logistic regression analysis failed to demonstrate that MS was an independent predictor of adverse events. Conclusion: MS is common in patients with acute myocardial infarction. MS has no significant effect on the severity and prognosis of coronary artery in patients with acute myocardial infarction.