本文观察了镉对培养新生大鼠心肌细胞力学特性的影响。实验分对照组、镉作用组和镉加药物干预组。实验见到镉离子使培养心肌细胞的收缩最大速度、舒张最大速度、收缩力和搏动频率明显降低，且以收缩和舒张的最大速度降低为主，当培养液中镉离子浓度仅为１６４×１０４ｍｏｌ／Ｌ时，相对收缩速度和舒张速度分别降低为对照组的４０８３％和３８５７％，而镉浓度达到２１８×１０４ｍｏｌ／Ｌ时，才引起培养心肌细胞搏动频率减慢，减慢为对照组的７４３％，这些作用可通过换液得到恢复，且肾上腺素或钙可对抗镉的这种作用 In this paper, the effects of cadmium on the mechanical properties of cultured neonatal rat cardiomyocytes were observed. Experimental control group, cadmium group and cadmium plus drug intervention group. The experimental results showed that the maximum velocity of contraction, the maximum diastolic velocity, the contractile force and the pulsation frequency of cadmium ion in cultured cardiomyocytes were significantly decreased, and the maximum velocity of systole and diastole was decreased. When the concentration of cadmium in the culture medium was only 1.64 × 10 4mol / L, the relative velocity of contraction and diastolic velocities decreased to 4083% and 3857% of the control group, respectively, while the concentration of cadmium reached 218 × 104mol / L, it caused the cultured cardiomyocytes The pulsatile frequency slowed down to 74.3% of the control group, and these effects were restored by fluid exchange and the effect of adrenaline or calcium on cadmium