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1 材料和方法1.1 材料所有患者来自上海郊县的金山和奉贤地区,因中上腹不适来院行内镜检查的门诊患者.内镜检查活检组织取自胃底和胃窦(距幽门2 cm 处),其中胃窦组织行快速尿素酶检查,另一块胃窦组织及胃底组织进行 W-S 染色,所有作病理学检查的标本送至上海中山医院病理科统一切片、染色及阅片.两种方法同时阳性者诊断为幽门螺杆菌(Hp)感染.纳入标准除 Hp感染外,还包括年龄>18岁、签署知情同意书.排除标准为复合溃疡、上消化道出血者、有胃大部手术史者、检查前3 d 用过抗生素或抑酸药物者、青霉素过敏者、需长期服用非类固醇消炎药(NSAID)者、胃 MT 或其他肿瘤者、孕期妇女.自1997-02/1998-10共收集188例患者,随机进入 A 组和 B 组,其中 A 组
1 Materials and Methods 1.1 Materials All patients from Jinshan and Fengxian areas in suburban Shanghai and outpatients with endoscopy due to middle-to-upper abdominal discomfort were collected from the fundus and antrum (2 cm from the pylorus) ), In which the gastric antrum was examined by rapid urease, and another piece of gastric antrum and gastric fundus was stained by WS, and all the specimens for pathological examination were sent to the Department of Pathology, Shanghai Zhongshan Hospital, While positive were diagnosed as Helicobacter pylori (Hp) infection.Inclusion criteria In addition to Hp infection, but also include the age> 18 years old, signed informed consent.Exclusion criteria for the compound ulcer, upper gastrointestinal bleeding, a history of major gastric surgery Those who used antibiotics or acid-suppressing drugs in the previous 3 days, those who were allergic to penicillin, long-term use of non-steroidal anti-inflammatory drugs (NSAIDs), gastric MT or other tumors, and pregnant women. Since 1997-02 / 1998-10 A total of 188 patients were enrolled and randomized into Groups A and B, Group A