哌嗪盐类自1949年开始用作驱虫剂后,已被认为是治疗蛔虫和蛲虫的首选药物。关于该药引起的神经毒性副反应极少报道。本文作者报告一例使用一般常用剂量后发生神经毒性副反应。患者系12岁女孩,体重30公斤,睡前服枸橼酸哌嗪(驱蛔灵)3克治疗蛔虫感染。次早患者不能在床上坐起,呼吸每分钟10次,其他体征和血压均正常。神经系检查发现眼球水平震颤,肌强力普遍性减弱,无人扶持不能站立或坐,张力减退,腱反 Piperazine salts have been considered as the drug of choice for the treatment of roundworms and pinworms since they were used as insect repellents in 1949. Neurotoxic side effects caused by the drug are rarely reported. The authors report a case of neurotoxicity after using a commonly used dose. The patient is a 12-year-old girl weighing 30 kg and taking 3 grams of piperazine citrate (propranolol) before going to bed to treat a roundworm infection. The next morning, patients can not sit up in bed, breathing 10 times per minute, other signs and blood pressure were normal. Nervous system examination found that the eye level tremor, weakened generality of muscle strength, no one can not stand or support, tension loss, tendon