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本文将1979年1月～1986年6月间的门诊初治涂阳病人,根据病人实际情况(距门诊治疗点远近)分为全面监督化疗组和全程管理化疗组两组进行治疗。现将资料完整的284例进行分析。 284例,男136例;女148例。监督化疗组127例;全程管理化疗组157例。治疗方案以HRS为主,部分采用RHSE或RHSZ(均为每日用药,H0.3,R0.45,S0.75,E0.75,Z1.5。其中S用于强化阶段2～3月),全疗程为12月。疗效观察以痰菌为主、初诊3次厚涂片查痰,以后每月1次。全疗程中断用药达30天,或一次中断用药在15天以上者,为不规则用药。疗程结束痰涂片连续三次阴性为阴转,以第二次阴性计算时间。结果监督化疗组痰菌阴转123例(96.9％);全程管理化疗组阴转152例(96.8％)。
This article from January 1979 to June 1986 outpatient smear-positive patients, according to the actual situation of patients (from the out-patient point of treatment) is divided into fully controlled chemotherapy group and the entire management of chemotherapy group two groups for treatment. 284 cases are now complete data analysis. 284 cases, 136 males and 148 females. 127 cases were supervised by chemotherapy group; 157 cases were managed by chemotherapy. The treatment regimen is mainly HRS, partly using RHSE or RHSZ (all daily medication, H0.3, R0.45, S0.75, E0.75, Z1.5, where S is used for strengthening period from March to March) , The whole course of treatment is December. Observation of the main sputum bacteria, the first three thick smear sputum check, after a month. The whole course of treatment interruption of up to 30 days, or an interruption of medication in more than 15 days for irregular medication. End of sputum smear three consecutive negative for the negative, with the second negative time. Results In the chemotherapy group, 123 cases (96.9%) were sputum negative conversion; and 152 cases (96.8%) in the whole management chemotherapy group.