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目的冠心病、心绞痛是心血管内科常见病,易致心肌梗死,我院采用低分子肝素钙,阿托伐他汀联合治疗不稳定型心绞痛,效果满意。方法选择不稳定型心绞痛患者58例,随机分为二组,每组29例,在常规治疗基础上应用低分子肝素钙、阿托伐他汀治疗,观察各组疗效。结果观察组治疗后胆固醇、甘油三酯、低密度脂蛋白胆固醇均较治疗前明显下降(P<0.1)。心绞痛发作情况较对照组明显降低(P<0.1)。结论低分子肝素钙,联合阿托伐他汀对降低血脂和控制不稳定心绞痛的发作疗效显著,减少心脑血管事件作用佳,治疗过程无严重不良反应,具有良好的安全性和耐受性。
Purpose of coronary heart disease, angina pectoris is a common disease of cardiovascular medicine, easy to cause myocardial infarction, low molecular weight heparin calcium in our hospital, atorvastatin combined treatment of unstable angina, the effect is satisfactory. Methods Fifty-eight patients with unstable angina pectoris were randomly divided into two groups (n = 29 in each group). On the basis of routine treatment, they were treated with low molecular weight heparin and atorvastatin, and the curative effect of each group was observed. Results After treatment, cholesterol, triglyceride and low density lipoprotein cholesterol in the observation group were significantly lower than those before treatment (P <0.1). Angina pectoris was significantly lower than the control group (P <0.1). Conclusion Low molecular weight heparin and atorvastatin have significant effects on lowering blood fat and controlling unstable angina pectoris. They are effective in reducing cardiovascular and cerebrovascular events and have no serious side effects during treatment. They have good safety and tolerability.