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目的:探讨山绿茶三种不同炮制品对实验性鹌鹑高脂血症的降血脂作用。方法:用鹌鹑以高脂饲料造模,灌胃给予山绿茶三种不同炮制品(原工艺炮制品、自炒品、烘干品),连续14 d,测定血清中TC、TG、LDL-C、HDL-C的含量;测定自炒品、烘干品的急性毒性(MTD)。结果:原工艺炮制品三个剂量对TC均有明显的降低作用(P<0.01),对TG、LDL-C和HDL-C则无明显影响;自炒品三个剂量对TC、TG均有明显的降低作用(P<0.01),对LDL-C和HDL-C无明显影响;烘干品三个剂量对TC均有明显的降低作用(P<0.01),对LDL-C和HDL-C无明显影响,烘干品小剂量对TG有一定的降低作用(P<0.05)。山绿茶自炒品MTD为80 g生药/kg;烘干品MTD为120 g生药/kg。结论:三种炮制品对高脂血症的防治效果为自炒品>烘干品>原工艺炮制品。急性毒性结果表明山绿茶自炒品、烘干品毒性低。
Objective: To investigate the hypolipidemic effect of three different green tea processed products on experimental quail hyperlipidemia. Methods: Using quail to make model with high-fat diet, three different medicinal products of mountain green tea were given by gavage for 14 days. The contents of TC, TG, LDL-C , HDL-C content; determination of self-fried goods, dried goods acute toxicity (MTD). Results: Three doses of the finished product had a significant reduction in TC (P <0.01), but no significant effect on TG, LDL-C and HDL-C (P <0.01), but had no significant effect on LDL-C and HDL-C; the three doses of dried products had a significant reduction on TC (P <0.01), but LDL-C and HDL- No significant effect, a small dose of dried products on the TG decreased (P <0.05). Mountain green tea since the speculation MTD 80 g crude drug / kg; dried MTD of 120 g crude drug / kg. Conclusion: The control effect of three processed products on hyperlipidemia is self-scorching product> dried product> original product. Acute toxicity results show that mountain green tea since the fried products, low toxicity of dried goods.